Despite handing out over $700 million in donations this year, the gift to Human Rights Watch is the largest single donation the financier has ever made.
"Human rights underpin our greatest aspirations: they're at the heart of open societies," Soros said in a statement.
Soros, who has an estimated net worth of $12 billion, made his fortune betting against the pound sterling when it fell out of the European Exchange Rate Mechanism in 1992.
When announcing his donation the financier took a moment to criticize the Bush administration for damaging America's image across the globe:
"I'm afraid the United States has lost the moral high ground under the Bush administration, but the principles that Human Rights Watch promotes have not lost their universal applicability," he said.
"It's an American organization and that has become a drawback because America has lost the moral high ground for promoting human rights," he added in an interview with National Public Radio. "So I want the organization to become truly international with maybe the American members in the minority."
The grant will match up to $100 million in private donations over the next ten years, but will not be withheld if the charity fails to meet the goal.
Human Rights Watch executive director Kenneth Roth said the money would go towards making the organization truly global by filling reporting gaps in the "emerging global South," including Asia and Latin America.
"In an increasingly multi-polar world, we must ensure that Human Rights Watch's message resonates in the most influential capitals around the globe," he said in a statement.
Founded in 1978 to draw attention to human rights violations in the Soviet Union and Eastern Europe, the New York-based organization now publishes over 100 reports a year on human rights conditions across the globe.
Soros, who had previously been committed to donating all of his wealth during his lifetime, now runs the Open Society Institute foundation which will continue giving after his death.
